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Aintzane Pikabea, Jose Ramos and Jacqueline Forcada Production of Cationic Nanogels with Potential Use in Controlled Drug Delivery Particle & Particle Systems Characterization 31

Version of Record online: 21 OCT 2013 | DOI: 10.1002/ppsc.201300265

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The analysis of the swelling behavior of poly(2-(diethylamino)ethyl) methacrylate (PDEAEMA)-based nanogel particles, presenting a dual-dependent thermo- and pH-sensitivity tunable with the ionic strength, indicates that these nanogels undergo a unique transition from a swollen to a collapsed state at physiological conditions. This tunable and dual sensitivity makes them attractive and potentially applicable in the field of controlled drug delivery.

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