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Elżbieta Kamysz, Beata Mickiewicz, Wojciech Kamysz, Sylwia Bielińska, Sylwia Rodziewicz-Motowidło and Jerzy Ciarkowski Synthesis, biological activity and solution structure of new analogues of the antimicrobial Gramicidin S Journal of Peptide Science 17

Version of Record online: 25 OCT 2010 | DOI: 10.1002/psc.1314

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The work describes the synthesis, antimicrobial and hemolytic activities as well as solution structures of three new analogues of Gramicidin S designed with the purpose of perturbing their amphipathic moments. A novel approach to the synthesis of head-to-tail cyclopeptides has been presented.

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