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Alayne L. Schroll, Robert J. Hondal and Stevenson Flemer Jr. 2,2′-Dithiobis(5-nitropyridine) (DTNP) as an effective and gentle deprotectant for common cysteine protecting groups Journal of Peptide Science 18

Article first published online: 14 NOV 2011 | DOI: 10.1002/psc.1403

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The scope and limitations of a gentle and universal cysteine S-deprotection technique is presented in which all commercially available Cys protecting groups are assayed as to the deprotective potentital toward DTNP-mediated removal conditions.

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