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Adriano Mollica, Roberto Costante, Azzurra Stefanucci, Francesco Pinnen, Gino Lucente, Stefano Fidanza and Stefano Pieretti Antinociceptive profile of potent opioid peptide AM94, a fluorinated analogue of biphalin with non-hydrazine linker Journal of Peptide Science 19

Version of Record online: 8 NOV 2012 | DOI: 10.1002/psc.2465

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The antinociceptive profile of AM94 has been evaluated by in vivo nociception tests, in rats (tail flick test) and in mice (formalin test). Result have been compared with those of biphalin and morphine. Variable-temperature 1H NMR experiments and energy minimization were also carried out.

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