E-mail

E-mail a Wiley Online Library Link

Jinfeng Zhao, Chuanzhi Sun, Nan Sun, Lin Meng and Dezhan Chen Theoretical study on the mechanism of the reaction for alkene hydroaminations catalyzed by chiral aldehyde International Journal of Quantum Chemistry 113

Version of Record online: 4 JUN 2013 | DOI: 10.1002/qua.24483

Thumbnail image of graphical abstract

Alkene hydroamination catalyzed by chiral aldehyde, based on temporary intramolecularity, is a new concept in chemistry. To clarify the reaction mechanism, alkene hydroamination of N-benzylhydroxylamine and secondary allylic amine is modeled using DFT. The chiral catalyst allows the key formation of a mixed aminal species, resulting in a facile intramolecular hydroamination event. Simple aldehyde precatalyst enables the synthesis of vicinal diamines through temporary intramolecularity.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH