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Jie Lu, Monty Liong, Jeffrey I. Zink and Fuyuhiko Tamanoi Mesoporous Silica Nanoparticles as a Delivery System for Hydrophobic Anticancer Drugs Small 3

Version of Record online: 13 JUN 2007 | DOI: 10.1002/smll.200700005

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Special delivery: The hydrophobic anticancer drug camptothecin was incorporated into fluorescent mesoporous silica nanoparticles (see image) and delivered to various cancer cells to induce cell death. These results suggest a method to overcome the insolubility problem of many anticancer drugs, which is considered to be one of the major challenges in cancer therapy.

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