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Gregor Heiss, Vidmantes Lapiene, Florian Kukolka, Christof M. Niemeyer, Christoph Bräuchle and Don C. Lamb Single-Molecule Investigations of a Photoswitchable Nanodevice Small 5

Version of Record online: 4 MAR 2009 | DOI: 10.1002/smll.200801549

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Photocontrollable DNA Nanodevices: Using structurally addressable DNA as a scaffold, an optically addressable nanodevice with the photoconvertible protein Dronpa and Atto647N is fabricated (see image). The device is characterized using single-molecule spectroscopy. As nanodevices are well suited for the investigation of cellular processes, the ability to optically detect and address this nanodevice in the context of a living cell is shown.

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