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Bin Kang, Decai Yu, Yaodong Dai, Shuquan Chang, Da Chen and Yitao Ding Cancer-Cell Targeting and Photoacoustic Therapy Using Carbon Nanotubes as “Bomb” Agents Small 5

Version of Record online: 9 MAR 2009 | DOI: 10.1002/smll.200801820

Thumbnail image of graphical abstract

Carbon nanotube photoacoustic “bomb” agents trigger an explosion in water and generate strong shockwaves under the irradiation of a 1064-nm millisecond pulsed laser (upper image). Based on this large photoacoustic effect, cancer cells are selectively destroyed by the strong shockwave explosion of nanotubes inside cells. The necrotic cells (bottom right) exhibit a cracked morphology and structure that differ from living cells (bottom left).

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