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Thomas Crouzier, Anna Szarpak, Thomas Boudou, Rachel Auzély-Velty and Catherine Picart Polysaccharide-Blend Multilayers Containing Hyaluronan and Heparin as a Delivery System for rhBMP-2 Small 6

Article first published online: 12 FEB 2010 | DOI: 10.1002/smll.200901728

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Polyelectrolyte multilayer films made from poly(L-lysine) and a polysaccharide blend of hyaluronan (HA) and heparin (HEP) are observed by AFM and characterized by infrared spectroscopy. A preferential incorporation of HEP over HA in the film is observed, leading to variations in the film morphology and thickness.

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