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Alaa A. A. Aljabali, Frank Sainsbury, George P. Lomonossoff and David J. Evans Cowpea Mosaic Virus Unmodified Empty Viruslike Particles Loaded with Metal and Metal Oxide Small 6

Article first published online: 8 MAR 2010 | DOI: 10.1002/smll.200902135

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Empty (devoid of RNA) viruslike particles (eVLPs) of Cowpea mosaic virus can now be obtained readily. CPMV can encapsulate, within the protein capsid, cobalt or iron oxide by environmentally benign processes. The external surface also remains amenable to chemical modification. The development of eVLPs for targeted delivery of therapeutic agents is now a reality.

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