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Bin Kang, Shuquan Chang, Yaodong Dai, Decai Yu and Da Chen Cell Response to Carbon Nanotubes: Size-Dependent Intracellular Uptake Mechanism and Subcellular Fate Small 6

Article first published online: 27 SEP 2010 | DOI: 10.1002/smll.201001260

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The intracellular uptake and subcellular localization of carbon nanotubes strongly depend on the physical size of the materials. Multiwalled carbon nanotubes (MWNTs; 0.5–2 μm in length, 10–30 nm in diameter) are excluded from the interior of the cell; long single-walled carbon nanotubes (L-SWNTs) of length 100–200 nm (1–3 nm in diameter) are only internalized into cytoplasm, whereas short ones (S-SWNTs) of length 50–100 nm partly reside in the cell nucleus.

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