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Scott M. Tabakman, Zhuo Chen, Hernan Sanchez Casalongue, Hailiang Wang and Hongjie Dai A New Approach to Solution-Phase Gold Seeding for SERS Substrates Small 7

Article first published online: 3 JAN 2011 | DOI: 10.1002/smll.201001836

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A solution-phase method to seed nanoparticle precursors and grow plasmonic gold films on a wide variety of unmodified substrates is presented. The resulting gold-on-gold films exhibit a strong surface-enhanced Raman scattering effect, with enhancement factors of ≈107 observed stably and uniformly over large areas. Combined with carbon nanotube Raman labels, the films afford highly sensitive detection of a cancer biomarker protein.

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