Do-Myoung Kim, Mitsuo Umetsu, Kyo Takai, Takashi Matsuyama, Nobuhiro Ishida, Haruo Takahashi, Ryutaro Asano and Izumi Kumagai Enhancement of Cellulolytic Enzyme Activity by Clustering Cellulose Binding Domains on Nanoscaffolds Small 7
Heteroclustering of recombinant cellu-lase modules on streptavidin and nanoparticles results in significant improvements in the enzyme’s degradation activity for water-insoluble substrates. The clustering of multiple cellulose-binding domains (CBDs) on CdSe nanoparticles generates a significant increase in activity relative to that of the native free enzyme. A new design for artificial cellulosomes with multiple CBDs on noncellulosome-derived scaffold structures is proposed.
Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf