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Jennifer S. Park, Joseph M. Kinsella, Danielle D. Jandial, Stephen B. Howell and Michael J. Sailor Cisplatin-Loaded Porous Si Microparticles Capped by Electroless Deposition of Platinum Small 7

Version of Record online: 1 JUN 2011 | DOI: 10.1002/smll.201100438

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Porous silicon-based microparticles are used to load cisplatin, an anti-cancer drug, using reductive chemistry that caps the drug into the pores by partially converting cisplatin into metallic platinum. Cellular toxicity with ovarian cancer cells demonstrates an enhanced toxic effect in comparison to free drugs.

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