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Katrin G. Witten, Claudia Rech, Thomas Eckert, Samir Charrak, Walter Richtering, Lothar Elling and Ulrich Simon Glyco-DNA–Gold Nanoparticles: Lectin-Mediated Assembly and Dual-Stimuli Response Small 7

Version of Record online: 8 JUN 2011 | DOI: 10.1002/smll.201100492

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The formation and properties of glyco-DNA–gold nanoparticles (NP) with a multivalent presentation of DNA-glyco ligands is presented. These particles are equipped with two reversible binding modes, which enable reversible dissociation by two independent external stimuli: temperature-induced DNA duplex melting and displacement of the DNA-glyco ligands from the carbohydrate recognition domains with free sugar.

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