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Hannah Lomas, Angus P. R. Johnston, Georgina K. Such, Zhiyuan Zhu, Kang Liang, Martin P. Van Koeverden, Siripong Alongkornchotikul and Frank Caruso Polymersome-Loaded Capsules for Controlled Release of DNA Small 7

Version of Record online: 4 JUL 2011 | DOI: 10.1002/smll.201100744

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A layer-by-layer capsule system subcompartmentalized with pH-responsive polymersomes loaded with Cy5-labeled plasmid DNA is formed for use as a novel drug-delivery carrier for the controlled release of DNA. The DNA is released from the capsules in response to pH changes between physiological and endocytic conditions.

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