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Santosh K. Misra, Paturu Kondaiah, Santanu Bhattacharya and C. N. R. Rao Graphene as a Nanocarrier for Tamoxifen Induces Apoptosis in Transformed Cancer Cell Lines of Different Origins Small 8

Version of Record online: 18 NOV 2011 | DOI: 10.1002/smll.201101640

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An amphiphile (PY+-Chol) aids the dispersion of graphene (GR) in water. The resulting suspension is able to efficiently solubilize a breast-cancer drug, Tamoxifen Citrate (TmC). TmC–GR–PY+-Chol suspension is a better and more selective apoptotic agent than free TmC or TmC–PY+-Chol suspensions against transformed cancer cells, making the former a promising system for use in cancer therapy.

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