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Alaaldin M. Alkilany, Alia Shatanawi, Timothy Kurtz, Ruth B. Caldwell and R. William Caldwell Toxicity and Cellular Uptake of Gold Nanorods in Vascular Endothelium and Smooth Muscles of Isolated Rat Blood Vessel: Importance of Surface Modification Small 8

Article first published online: 15 FEB 2012 | DOI: 10.1002/smll.201101948

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Intravascular injection is the main route of nanoparticle administration. Little is known about the potential adverse effects of nanoparticles on blood vessels. Using gold nanorods with different surface chemistry and isolated rat aortic rings, the adverse effects of nanoparticles on blood vessels are evaluated as a function of their surface chemistry.

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