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Armando Hernandez-Garcia, Marc W. T. Werten, Martien Cohen Stuart, Frits A. de Wolf and Renko de Vries Coating of Single DNA Molecules by Genetically Engineered Protein Diblock Copolymers Small 8

Version of Record online: 3 AUG 2012 | DOI: 10.1002/smll.201200939

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Biosynthetic protein diblock copolymers are designed to form stable protein-coated flexible nanorods consisting of single plasmid DNA molecules, reminiscent of cylindrical viruses. The protein coating forms a polymer brush that prevents inter- and intramolecular aggregation of DNA molecules. The controlled coating of single DNA molecules modulates their physical properties and interactions.

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