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Dorota Napierska, Rozenn Quarck, Leen C. J. Thomassen, Dominique Lison, Johan A. Martens, Marion Delcroix, Benoit Nemery and Peter H. Hoet Amorphous Silica Nanoparticles Promote Monocyte Adhesion to Human Endothelial Cells: Size-Dependent Effect Small 9

Article first published online: 8 OCT 2012 | DOI: 10.1002/smll.201201033

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The effect of amorphous silica nanoparticles (SiO2-NPs) of different sizes on endothelial cells function is examined in vitro. Human endothelial cells are incubated with SiO2-NPs in the presence or not of triple cell co-cultures. The results show that SiO2-NPs enhance the adhesive properties of endothelial cells. This process is modified by the size of the nanoparticle and the presence of other co-cultured cells.

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