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Krishnendu Saha, Sung Tae Kim, Bo Yan, Oscar R. Miranda, Felix S. Alfonso, Denis Shlosman and Vincent M. Rotello Surface Functionality of Nanoparticles Determines Cellular Uptake Mechanisms in Mammalian Cells Small 9

Article first published online: 13 SEP 2012 | DOI: 10.1002/smll.201201129

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Surface functionalization of cationic gold nanoparticles is an important determinant of the mechanism of cellular uptake. It is shown that changes in functionality alter endocytotic pathways, providing a potential strategy for enhancing selectivity in delivery applications.

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