E-mail

E-mail a Wiley Online Library Link

Kevin J. Freedman, Arangassery R. Bastian, Irwin Chaiken and Min Jun Kim Solid-State Nanopore Detection of Protein Complexes: Applications in Healthcare and Protein Kinetics Small 9

Article first published online: 17 OCT 2012 | DOI: 10.1002/smll.201201423

Thumbnail image of graphical abstract

A nanopore platform is shown to detect various sub-populations of protein-protein complexes as well as dissociate freely translocating proteins generating unique current signatures. The proposed method of locally unbinding protein molecules allows enhancement of the specificity of diagnostic nanopore sensors as well as the abiltiy to study the recently unbound state of a protein. These applications underscore the label-free, inexpensive, electrical detection scheme offered by nanopore-based devices.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

Choose captcha format: Image or Audio. Click here if you need help.

SEARCH