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Mariana B. Oliveira, Christiane L. Salgado, Wenlong Song and João F. Mano Combinatorial On-Chip Study of Miniaturized 3D Porous Scaffolds Using a Patterned Superhydrophobic Platform Small 9

Version of Record online: 21 NOV 2012 | DOI: 10.1002/smll.201201436

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Combinatorial array-based study of 3D porous scaffolds using biomimetic-inspired platforms is performed by fabricating polymeric porous structures in wettable patterns of a superhydrophobic surface. Scaffolds’ elastic modulus, porosity and protein adsorption rates are measured on-chip. The analysis of the combinatorial effect of these distinct variables in the behavior of two types of cells is carried out by non-destructive image-based methods.

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