E-mail a Wiley Online Library Link

Vadim V. Sumbayev, Inna M. Yasinska, Cesar Pascual Garcia, Douglas Gilliland, Gurprit S. Lall, Bernhard F. Gibbs, David R. Bonsall, Luca Varani, François Rossi and Luigi Calzolai Gold Nanoparticles Downregulate Interleukin-1β-Induced Pro-Inflammatory Responses Small 9

Version of Record online: 30 OCT 2012 | DOI: 10.1002/smll.201201528

Thumbnail image of graphical abstract

Interleukin 1 beta (IL-1β)-dependent inflammatory disorders pose a serious medical burden worldwide. Here it is shown for the first time that gold nanoparticles specifically downregulate cellular responses induced by IL-1β. These results indicate that the anti- inflammatory activity of gold nanoparticles is associated with an extracellular interaction with IL-1β, thus opening potentially novel options for further therapeutic applications.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field