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Xiaoning Li, Fang Wen, Brian Creran, Youngdo Jeong, Xinrong Zhang and Vincent M. Rotello Colorimetric Protein Sensing Using Catalytically Amplified Sensor Arrays Small 8

Version of Record online: 7 SEP 2012 | DOI: 10.1002/smll.201201549

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Catalytically active iron oxide nanoparticles are used as recognition elements and signal amplifiers for the array-based colorimetric sensing of proteins. Interactions between cationic monolayers on the Fe3O4 NPs and analyte proteins differentially modulates the peroxidase-like activity of Fe3O4 NPs, affording catalytically amplified colorimetric signal patterns that enable the detection and identification of proteins at 50 nM.

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