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Phyllis F. Xu, Albert M. Hung, Hyunwoo Noh and Jennifer N. Cha Switchable Nanodumbbell Probes for Analyte Detection Small 9

Article first published online: 8 OCT 2012 | DOI: 10.1002/smll.201201721

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Nanodumbbell gold nanoparticle (AuNP) dimers connected by DNA show significant change in interparticle distance in the presence of a specific analyte, ATP. The nanodumbbell begins in an extended state, but after the addition of the analyte, the DNA connecting the AuNPs forms a stable hairpin, which causes a large decrease in the interparticle distance.

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