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Verena C. Stimberg, Johan G. Bomer, Iris van Uitert, Albert van den Berg and Séverine Le Gac High Yield, Reproducible and Quasi-Automated Bilayer Formation in a Microfluidic Format Small 9

Article first published online: 9 NOV 2012 | DOI: 10.1002/smll.201201821

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A microfluidic platform is presented for experimentation on planar cell membrane models and membrane proteins, using a combination of electrical and optical techniques. The applicability of the device is demonstrated for in-depth studies on membrane properties; confocal imaging of phase separation in ternary membrane systems; single protein measurements; and indirect assessment of membrane property alterations using the sensitivity of gramicidin to its environment.

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