Katrin Vogel, Maximilian Glettenberg, Hendrik Schroeder and Christof M. Niemeyer DNA-Modification of Eukaryotic Cells Small 9
A novel bioorthogonal method for the modification of cells with single-stranded DNA oligomers is compared to alternative chemistries. The method based on oxime ligation offers high labeling efficacy, specificity, and mildness to avoid cell damage. DNA-modified cells can be selectively immobilized on solid supports or assembled into small cell clusters with the aid of DNA hybridization.
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