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Chang-Sheng Chen, Xiao-Ding Xu, Ya Wang, Juan Yang, Hui-Zhen Jia, Han Cheng, Chih-Chang Chu, Ren-Xi Zhuo and Xian-Zheng Zhang A Peptide Nanofibrous Indicator for Eye-Detectable Cancer Cell Identification Small 9

Version of Record online: 6 DEC 2012 | DOI: 10.1002/smll.201201928

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Naked-eye judgment of cancer cells with a peptide nanofibrous indicator (NFI) is demonstrated. The NFI is achieved by integrating a borono-peptide (BP) and a catechol dye through specific interaction and self-assembly. The NFI interacts with cell-surface overexpressed sialyl Lewis X (sLex) and is capable of distinguishing cancerous and healthy cells through a macroscopic color change.

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