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Bingbing Sun, Xiang Wang, Zhaoxia Ji, Ruibin Li and Tian Xia NLRP3 Inflammasome Activation Induced by Engineered Nanomaterials Small 9

Version of Record online: 23 NOV 2012 | DOI: 10.1002/smll.201201962

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Mechanisms of NLRP3 inflammasome activation induced by engineered nanomaterials (ENMs): the physicochemical properties of ENMs that can be linked to NLRP3 inflammasome activation are reviewed. The elucidation of mechanisms of ENM–NLRP3 inflammasome interaction will help to develop safer ENMs and a potential therapy for ENM-induced adverse health effects.

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