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Hadi Shafiee, Muntasir Jahangir, Fatih Inci, ShuQi Wang, Remington B. M. Willenbrecht, Francoise F. Giguel, Athe M. N. Tsibris, Daniel R. Kuritzkes and Utkan Demirci Acute On-Chip HIV Detection Through Label-Free Electrical Sensing of Viral Nano-Lysate Small 9

Article first published online: 27 FEB 2013 | DOI: 10.1002/smll.201202195

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There is an unmet clinical need to detect HIV-1 at acute infection stage where current antibody based point-of-care (POC) technologies are not effective due to the low concentration of antibodies. To overcome this clinical diagnostic barrier, a simple, fast, and affordable diagnostic tool is developed that enables HIV-1 detection during the acute stage of the disease using the unique electrical signature of viral nano-lysates.

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