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Nianxi Zhao, Jian You, Zihua Zeng, Chun Li and Youli Zu An Ultra pH-Sensitive and Aptamer-Equipped Nanoscale Drug-Delivery System for Selective Killing of Tumor Cells Small 9

Article first published online: 23 APR 2013 | DOI: 10.1002/smll.201202694

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Using aptamer technology, an innovative ultra pH-sensitive nanoscale drug-delivery system is developed that selectively kills lymphoma tumor cells with no effects on off-target cells. The successful in vitro tests reported here represent an important step in the development of next-generation targeted cancer therapeutics.

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