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Jie Song, Zhao Zhang, Shuai Zhang, Lei Liu, Qiang Li, Erqing Xie, Kurt Vesterager Gothelf, Flemming Besenbacher and Mingdong Dong Isothermal Hybridization Kinetics of DNA Assembly of Two-Dimensional DNA Origami Small 9

Article first published online: 22 FEB 2013 | DOI: 10.1002/smll.201202861

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Direct investigation of the kinetics of multistrand DNA hybridization events on DNA origami nanopores under the defined isothermal conditions is performed via thermally controlled atomic force microscopy in combination with nanomechanical spectroscopy, with forces controlled in the pico Newton range.

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