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Heng Liu, Hui Yang, Xian Hao, Haijiao Xu, Yi Lv, Debao Xiao, Hongda Wang and Zhiyuan Tian Development of Polymeric Nanoprobes with Improved Lifetime Dynamic Range and Stability for Intracellular Oxygen Sensing Small 9

Article first published online: 21 MAR 2013 | DOI: 10.1002/smll.201203127

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Core-shell-type oxygen nanosensors with optimized formats are developed. They are characterized by their relatively small diameter (<50 nm), biocompatible and protective shells, covalent-attachment-imparted leak-free construction, improved lifetime dynamic range (up to 44 μs), and excellent storage stability and photostability. Their facile cell uptake and ability to sense intracellular oxygen are confirmed.

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