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Dong Hoon Choi, Ramesh Subbiah, Ik Hwan Kim, Dong Keun Han and Kwideok Park Dual Growth Factor Delivery Using Biocompatible Core–Shell Microcapsules for Angiogenesis Small 9

Article first published online: 15 APR 2013 | DOI: 10.1002/smll.201300427

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Core–shell microcapsules are fabricated from immiscible, biocompatible poly(L-lactic-co-glycolic acid) (PLGA) and alginate by using an electrodropping system. They hold the angiogenic growth factors (GFs) vascular endothelial GF (VEGF) in the shell alginate and platelet-derived GF (PDGF) in the core PLGA. The release profile of biomolecules is tunable by employing layer-by-layer assembly or by changing the polymer molecular weight.

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