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Xiangyuan Ouyang, Jiang Li, Huajie Liu, Bin Zhao, Juan Yan, Yinzhou Ma, Shoujun Xiao, Shiping Song, Qing Huang, Jie Chao and Chunhai Fan Rolling Circle Amplification-Based DNA Origami Nanostructrures for Intracellular Delivery of Immunostimulatory Drugs Small 9

Version of Record online: 24 APR 2013 | DOI: 10.1002/smll.201300458

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Several single-stranded scaffold DNA, obtained from rolling circle amplification (RCA), are folded by different staples to form DNA nanoribbons. These DNA nanoribbons are rigid, simple to design, and cost-effective drug carriers, which are readily internalized by mammalian cells and show enhanced immunostimulatory activity.

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