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Hengbin Zhang, Qing Zhao, Zhipeng Tang, Song Liu, Qingtao Li, Zhongchao Fan, Fuhua Yang, Liping You, Xuemei Li, Jingmin Zhang and Dapeng Yu Slowing Down DNA Translocation Through Solid-State Nanopores by Pressure Small 9

Article first published online: 5 JUL 2013 | DOI: 10.1002/smll.201301263

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The effect of applied pressure on event duration distributions in 3 kb dsDNA translocation is systematically investigated. The effects of pressure magnitude and nanopore size on the length discrimination between 615 bp and 1.14 kbp dsDNA is studied. The pressure-controlled DNA translocation in solid-state nanopores makes a significant contribution to improve the temporal resolution in DNA single-molecule detection.

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