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Shuo Bai, Sisir Debnath, Kirsty Gibson, Barbara Schlicht, Lauren Bayne, Michele Zagnoni and Rein V. Ulijn Biocatalytic Self-Assembly of Nanostructured Peptide Microparticles using Droplet Microfluidics Small 10

Article first published online: 5 AUG 2013 | DOI: 10.1002/smll.201301333

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Microfluidic uniformly-sized, nanostructured peptide microparticles are generated by exploiting the ability of enzymes to serve both as catalysts, to control self-assembly within monodisperse, surfactant-stabilized water-in-oil microdroplets, and as destabilizers of emulsions interfaces, to enable facile transfer of produced microparticles to water. This approach combines the advantages of biocatalytic self-assembly with the compartmentalization properties enabled by droplet microfluidics.

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