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George Pasparakis Light-Induced Generation of Singlet Oxygen by Naked Gold Nanoparticles and its Implications to Cancer Cell Phototherapy Small 9

Article first published online: 1 JUL 2013 | DOI: 10.1002/smll.201301365

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Generation of singlet oxygen by direct irradiation of naked gold nanoparticles is observed using either continuous wave or pulsed laser sources. The underlying mechanism involves plasmon- and hot-electron-mediated reaction pathways and 1O2 seems to significantly amplify the overall death rates during photothermal treatment of cancer cell lines in vitro.

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