E-mail

E-mail a Wiley Online Library Link

Jianfeng Han, Qin Wang, Zhirong Zhang, Tao Gong and Xun Sun Cationic Bovine Serum Albumin Based Self-Assembled Nanoparticles as siRNA Delivery Vector for Treating Lung Metastatic Cancer Small 10

Article first published online: 19 SEP 2013 | DOI: 10.1002/smll.201301992

Thumbnail image of graphical abstract

Cationic bovine serum albumin based self-assembled nanoparticles are developed to deliver therapeutic siRNA to treat lung metastatic cancer. Interaction between the vehicles and the negatively charged blood components mediates an immediate aggregate formation. This aggregation leads to a primary lung accumulation via the filter effect of capillary beds and the simultaneous dissolution of the aggregates facilitates efficient intracellular siRNA delivery within the lung.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

Choose captcha format: Image or Audio. Click here if you need help.

SEARCH