E-mail

E-mail a Wiley Online Library Link

Benjamin M. Davis, Eduardo M. Normando, Li Guo, Lisa A. Turner, Shereen Nizari, Paul O'Shea, Stephen E. Moss, Satyanarayana Somavarapu and M. Francesca Cordeiro Topical Delivery of Avastin to the Posterior Segment of the Eye In Vivo Using Annexin A5-associated Liposomes Small 10

Version of Record online: 5 MAR 2014 | DOI: 10.1002/smll.201303433

Thumbnail image of graphical abstract

Annexin A5 significantly enhances uptake and transcytosis of liposomal drug carrier systems across multi-layered corneal epithelial barriers. Using a combination of in vitro and in vivo assays, it is demonstrated that Annexin A5 coated liposomes can be employed to deliver physiologically significant concentrations of Avastin to the posterior of the rat and rabbit eye after topical instillation.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH