Lucia A. Ruocco, Emilia Romano, Concetta Treno, Enza lacivita, Arra Claudio, Ugo A. Gironi-Carnevale, Domenica Travaglini, Marcello Leopoldo, Giovanni Laviola, Adolfo G. Sadile and Walter Adriani Emotional and risk seeking behavior after prepuberal subchronic or adult acute stimulation of 5-HT7-Rs in naples high excitability rats Synapse 68
Subchronic stimulation of 5-HT7-Rs during the prepuberal period (PND 31-44, by LP-211 at 0.5 mg/kg/day) increases EZM head-dips (i.e. riskseeking propensity) in adolescent NHE rats. Thus, increased ongoing dysinhibition was produced in a model for hyperactivity and impaired attention.
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