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Ao Zhan, Xin Xu, Ling Chen, Xuefeng Wang, Xie Yanfeng, Wei Dan, Yan Zhan and Quanhong Shi Decreased expression of Gab2 in patients with temporal lobe epilepsy and pilocarpine-induced rat model Synapse 68

Article first published online: 20 DEC 2013 | DOI: 10.1002/syn.21725

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In animal studies, the authors show that Gab2 expression was decreased at different time points after kindling compared to the controls and the lowest level of Gab2 expression occurred at 1 week. This finding of Gab2 suggests that it may play an important role in the pathogenesis of TLE.

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