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Peter Wend, Liang Fang, Qionghua Zhu, Jörg H Schipper, Christoph Loddenkemper, Frauke Kosel, Volker Brinkmann, Klaus Eckert, Simone Hindersin, Jane D Holland, Stephan Lehr, Michael Kahn, Ulrike Ziebold and Walter Birchmeier Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours The EMBO Journal 32

Article first published online: 4 JUN 2013 | DOI: 10.1038/emboj.2013.127

Hyperproliferation of tumour-propagating cells in squamous cell carcinoma depends on Wnt/β-catenin signalling, which induces an open chromatin state and expression of self-renewal genes.

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