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Douglas McCloskey, Bernhard Ø Palsson and Adam M Feist Basic and applied uses of genome-scale metabolic network reconstructions of Escherichia coli Molecular Systems Biology 9

Article first published online: 30 APR 2013 | DOI: 10.1038/msb.2013.18

This review summarizes the applications enabled by genome-scale models of metabolism for the bacterium E. coli. It provides an overview of the applications along with a critical assessment of their successes and limitations, and a perspective on likely future developments in the field.

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