Raweewan Thiramanas, Kulachart Jangpatarapongsa, Udom Asawapirom, Pramuan Tangboriboonrat and Duangporn Polpanich Sensitivity and specificity of PS/AA-modified nanoparticles used in malaria detection Microbial Biotechnology 6
Polystyrene (PS) nanoparticle copolymerized with acrylic acid (AA) and colored monomer (ALN8T) (PS/AA-ALN8T) was synthesized and used as a solid support of antibody specific to Plasmodium falciparum for malaria detection. Antibody immobilization was performed by three processes to compare the sensitivity and specificity. High sensitivity of 100% was obtained in all kinds of antibody coated PS/AA-ALN8T nanoparticles when tested with P. falciparum, while the antibody coated nanoparticles prepared from streptavidin-biotin interaction exhibited the highest specificity to P. falciparum.
Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf