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Mónica Barriuso-Iglesias, Carlos Barreiro, Alberto Sola-Landa and Juan F. Martín Transcriptional control of the F0F1-ATP synthase operon of Corynebacterium glutamicum: SigmaH factor binds to its promoter and regulates its expression at different pH values Microbial Biotechnology 6

Article first published online: 9 JAN 2013 | DOI: 10.1111/1751-7915.12022

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The ATP synthase operon atpBEFHAGDC is important since it provides ATP to the cells. We prove that the expression of this operon in Corynebacterium glutamicum is controlled by the sigma factor sigH. The purification of the SigH protein and its binding to the ATPase promoter sequence, confirmed by EMSA, proved this regulation. Besides, the sigH binding sequence has been defined.

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