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Davide Merulla, Vassily Hatzimanikatis and Jan Roelof van der Meer Tunable reporter signal production in feedback-uncoupled arsenic bioreporters Microbial Biotechnology 6

Article first published online: 15 JAN 2013 | DOI: 10.1111/1751-7915.12031

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Design of gene reporter circuits for assaying environmental toxicants is often based on an exploitation of naturally existing regulatory loops. Here we show how uncoupling the ArsR-controlled feedback loop benefits tunable reporter gene expression for arsenite bioreporters.

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