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Hang Wang, Binfeng Ji, Hongzhen Ren and Chun Meng The relationship between lysine 4 on histone H3 methylation levels of alcohol tolerance genes and changes of ethanol tolerance in Saccharomyces cerevisiae Microbial Biotechnology 7

Version of Record online: 30 APR 2014 | DOI: 10.1111/1751-7915.12121

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The result indicated that ethanol tolerance was likely acquired through epigenetic changes rather than DNA mutation. The traits acquired through DNA mutation should not disappear quickly because the natural spontaneous mutation rate is not always high and specific, whereas the traits acquired through H3K4 tri-methylation change often show instability along with the changes of the environment.

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