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Dan Ericson, Kristina Hamberg, Gunilla Bratthall, Gabriela Sinkiewicz-Enggren and Lennart Ljunggren Salivary IgA response to probiotic bacteria and mutans streptococci after the use of chewing gum containing Lactobacillus reuteri Pathogens and Disease 68

Article first published online: 2 JUL 2013 | DOI: 10.1111/2049-632X.12048

In this small-scale random controlled trial, the authors have tested the effect of the probiotic bacterium, Lactobacillus reuteri, instilled into chewing gum versus a placebo. They found that the probiotic intervention did indeed affect salivary IgA concentration thus indicating an effect on local immunity, and providing yet another effective approach to the delivery of probiotics.

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